PRF (Platelet-rich Fibrine)

 What is PRF?

 Platelet-Rich Fibrin (PRF) is a groundbreaking new technique in regenerative medicine that many patients are benefiting from. PRF is a meshwork of cytokines, growth factors, and cells that are harvested from a small amount of the patient’s own blood. This blood is spun at a specific rate and time to form a fibrin clot full of regenerative potential.

 What is PRF used for?

 PRF has many applications including the following:

 Prevention of dry sockets after wisdom tooth removal – PRF placed into an extraction site

• Regeneration of bone after tooth removal – PRF placed into an extraction site
• Soft tissue grafting – PRF placed over area of soft tissue deficiency to assist in soft tissue healing
• Regeneration of bone after removal of cysts and other maxillofacial pathology – PRF placed into bony defect
• Closure of oroantral communication/fistula – PRF placed over defect
• Sinus lifts – PRF placed over lifted sinus membrane to assist in bony fill and maintenance of sinus health
• Cosmetics/Skincare – Injectable PRF used for hair and skin rejuvenation and treatment of deep scarring and skin hyperpigmentation

  WHAT TO EXPECT FROM
  A PRF TREATMENT

  Here’s what to expect when you visit a CARE Esthetics clinic for PRF Treatment:

  1. Blood Extraction
     Premier, we will draw a small amount of your blood through a virtually painless procedure.
  2. Blood Centrifugation
     Your blood will be processed in a centrifuge and spun slowly to produce PRF, ensuring that the blood will not separate as much as PRP.
  3. PRF Collection & Injection
     The PRF will be collected from the vial through a syringe and injected into the treatment areas.

Why use PRF?

 Surgeons and patients alike are benefiting from the use of PRF in surgical applications. From increasing post-operative comfort to assisting in regeneration of natural tissues PRF offers vast advantages

• Significant decrease in patient discomfort. The use of PRF has been shown to reduce the risk of complications and restrictions a patient may experience. The result is a notable decrease in patient discomfort, post-surgical pain, and post-op bleeding.
• It’s 100% natural and safe and easy to produce. PRF is derived from a patient’s own blood and processed and optimized for their clinical benefit. The use of PRF does not require anticoagulants, bovine thrombin, or any other foreign materials or chemicals. This means that patients have nearly no risk of a foreign body reaction.
• PRF has been shown to result in significantly faster healing. This process generates a fibrin network that leads to more efficient cell migration and faster cell regeneration.

Impact of Platelet-Rich Fibrin on Mandibular Third Molar Surgery Recovery:

https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-019-0824-3

Efficacy of Platelet-Rich Fibrin After Mandibular Third Molar Extraction:

https://head-face-med.biomedcentral.com/articles/10.1186/s13005-015-0094-5  

Platelet rich fibrin in the management of established dry socket:

Srinivas Chakravarthi

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529189/

Effectiveness of platelet-rich fibrin in the management of pain and delayed wound healing associated with established alveolar osteitis (dry socket)

Ashish Sharma,

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727738/

Guided bone regeneration in staged vertical and horizontal bone augmentation using platelet-rich fibrin associated with bone grafts: a retrospective clinical study

https://journalimplantdent.springeropen.com/articles/10.1186/s40729-020-00266-y

De nombreuses études récentes ont montré l'intérêt et le potentiel des globules blancs dans la cascade inflammatoire, comme corollaire, une action importante dans les premiers jours de la stimulation des cellules ostéo-progénitrices. (Omar & Thomsen, biomatériaux, 2012, Kawazoe T, Cellule. Une greffe 2012)

Cela se fait avec la UNE-PRF ou Avancée-PRF.